How to Handle Constipation from GLP-1 Medications
Constipation is a common side effect experienced by individuals taking GLP-1 medications such as Ozempic, Wegovy, Mounjaro, and Zepbound. These medications work by slowing gastric emptying and reducing appetite, which can inadvertently lead to digestive issues, including constipation. At Trevi Medical, we prioritize a comprehensive approach to managing this side effect, ensuring our patients' comfort and the effectiveness of their weight loss journey.
Understanding the Cause
GLP-1 receptor agonists, while effective for weight loss and blood sugar control, can slow down the movement of food through the digestive tract. This delayed gastric emptying can result in fewer bowel movements and harder stools. Additionally, reduced food intake may lead to lower fiber consumption, further exacerbating constipation.
Trevi Medical's Approach to Managing Constipation
Our strategy encompasses dietary adjustments, hydration, supplementation, and, when necessary, medication modifications:
1. Increase Fiber Intake
Incorporating high-fiber foods such as leafy greens, legumes, and whole grains can add bulk to the stool and promote regular bowel movements. For those struggling to meet fiber requirements through diet alone, fiber supplements like psyllium husk may be beneficial.
2. Stay Hydrated
Adequate water intake is crucial. We recommend consuming at least 8–10 glasses of water daily to help soften stools and facilitate bowel movements.
3. Magnesium Citrate Supplementation
Magnesium citrate acts as an osmotic laxative, drawing water into the intestines and easing stool passage. It's a gentle option we often suggest to alleviate constipation.
4. Monitor and Adjust Medication Dosage
If constipation persists, we assess the GLP-1 medication dosage. Sometimes, a temporary dose reduction can alleviate symptoms. Additionally, we may introduce other peptides that support fat burning without intensifying gastrointestinal side effects.
5. Regular Physical Activity
Engaging in regular exercise stimulates intestinal activity. Even moderate activities like walking can significantly improve bowel regularity.
6. Consideration of Other Medications
In cases where lifestyle modifications are insufficient, we may explore medications such as lactulose, linaclotide (Linzess), or lubiprostone (Amitiza) to manage constipation effectively.
Personalized Care at Trevi Medical
At Trevi Medical, we understand that each patient's experience with GLP-1 medications is unique. Our individualized care plans are designed to address specific side effects like constipation, ensuring that your weight loss journey is both effective and comfortable.
If you're experiencing constipation while on GLP-1 medications, don't hesitate to reach out. Our team is here to provide support and tailored solutions to help you achieve your health goals.
