GLP-1 Weight Loss
Medically Supervised
At TREVI Longevity and Aesthetics, we offer medically supervised weight loss programs designed to help you achieve and maintain a healthy weight.
Get personalized, evidence-based treatments to support your weight loss journey.
Safe and Effective
Medical Weight Loss Programs
At our practice, medical weight loss is more than just a diet—it’s a customized, evidence-based approach designed to help you safely and sustainably reach your health goals.
We offer multiple pathways to support your unique body composition, metabolism, and preferences.
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Treatment Options Include:
GLP-1 Medications (e.g., semaglutide, tirzepatide):
These medications regulate appetite, blood sugar, and metabolic processes, helping you feel fuller longer and supporting weight loss.HCG + Low-Calorie Keto Diet:
Combines human chorionic gonadotropin (HCG) with a carefully monitored low-calorie ketogenic diet to target fat loss while preserving lean muscle.Prolon Fasting Mimicking Program:
A 5-day structured fasting plan that mimics the effects of fasting while allowing some caloric intake, resetting metabolic pathways and promoting sustainable weight loss.Peptide Therapy (as needed):
Used to preserve muscle mass during weight loss, especially if signs of muscle loss appear during monitoring. -
Tailored to You:
Every program is customized based on your body composition, health history, and goals, ensuring the safest and most effective approach for you.Variety of Options:
Whether you're interested in GLP-1 medications, HCG protocols, fasting-mimicking diets, or peptide support, we have solutions that fit your preferences and needs.Focus on Fat Loss, Not Muscle Loss:
Our monitoring ensures that weight loss comes from fat stores, not lean muscle, supporting long-term metabolic health.Holistic and Sustainable:
We emphasize long-term habits and lifestyle adjustments to help you maintain your results and overall wellness. -
Initial Consultation & Assessment:
We begin with an in-depth evaluation of your health, weight loss history, and personal goals.Customized Plan Development:
Based on your assessment, we select the best pathway—whether GLP-1 medications, HCG protocols, Prolon, or a combination—to ensure optimal outcomes.Ongoing Monitoring:
Regular check-ins help track progress, adjust your plan as needed, and monitor body composition (fat vs. muscle loss).Peptide Therapy (if needed):
If muscle loss is detected, peptide therapy may be introduced to support muscle retention and recovery.Flexible Scheduling:
Treatments like Prolon offer structured, manageable plans (e.g., 5-day cycles), while medications and other protocols are seamlessly integrated into your routine.Why Medical Supervision Matters:
Unsupervised weight loss programs can lead to nutrient deficiencies, muscle loss, and unsustainable results. With our medically guided approach, we ensure your journey is safe, effective, and supports long-term health.
Ozempic, Wegovy & More
GLP-1 Injections: Semaglutide
Semaglutide is an antidiabetic medication used for the treatment of type 2 diabetes and long-term weight management. Semaglutide acts like human glucagon-like peptide-1 (GLP-1) in that it increases insulin secretion, thereby increasing sugar metabolism.
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Semaglutide helps the pancreas release the right amount of insulin when blood sugar levels are high. It is FDA approved for improving glycemic control in patients with Type 2 diabetes (Ozempic) and for weight loss (Wegovy).
Studies show that Semaglutide can reduce appetite and cravings in addition to improving glycemic control. Some studies show negative side effects that may include nausea, diarrhea and even vomiting at higher dosage.
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Appetite & Satiety (GLP-1 + GIP)
Reduces hunger signals
Enhances fullness and delays gastric emptying
Supports blood sugar regulation
Fat Burning (Glucagon Receptor)
Increases energy expenditure
Stimulates lipolysis (fat breakdown)
May reduce fatty liver and visceral fat
Insulin Sensitivity (GLP-1 + GIP)
Improves insulin response and lowers fasting insulin
Helps stabilize glucose levels
May benefit PCOS, metabolic syndrome, and prediabetes
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Initial Consultation & Assessment:
We begin with an in-depth evaluation of your health, weight loss history, and personal goals.Customized Plan Development:
Based on your assessment, we select the best pathway—whether GLP-1 medications, HCG protocols, Prolon, or a combination—to ensure optimal outcomes.Ongoing Monitoring:
Regular check-ins help track progress, adjust your plan as needed, and monitor body composition (fat vs. muscle loss).Peptide Therapy (if needed):
If muscle loss is detected, peptide therapy may be introduced to support muscle retention and recovery.Flexible Scheduling:
Treatments like Prolon offer structured, manageable plans (e.g., 5-day cycles), while medications and other protocols are seamlessly integrated into your routine.Why Medical Supervision Matters:
Unsupervised weight loss programs can lead to nutrient deficiencies, muscle loss, and unsustainable results. With our medically guided approach, we ensure your journey is safe, effective, and supports long-term health.
Safe and Effective
GLP-1 Injections: Tirzepatide
Tirzepatide is a lot like Semaglutide, but with enhanced efficacy and additional properties. Compared to strict GLP-1 receptor agonists, Tirzepatide is nearly 33 times more likely to produce weight loss of 15% of total body weight in research studies. Among the GLP-1 agonist peptides for weight loss research, Tirzepatide is the heavyweight champion.
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Tirzepatide works via the GLP-1 receptor in the central nervous system to curb appetite. It works via the GIP receptor to boost insulin release and inhibit gastrin release. Gastrin speeds gastric emptying and thus its inhibition helps to slow GI motility to boost feelings of satiety and decrease feelings of hunger.
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Appetite & Satiety (GLP-1 + GIP)
Reduces hunger signals
Enhances fullness and delays gastric emptying
Supports blood sugar regulation
Fat Burning (Glucagon Receptor)
Increases energy expenditure
Stimulates lipolysis (fat breakdown)
May reduce fatty liver and visceral fat
Insulin Sensitivity (GLP-1 + GIP)
Improves insulin response and lowers fasting insulin
Helps stabilize glucose levels
May benefit PCOS, metabolic syndrome, and prediabetes
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Initial Consultation & Assessment:
We begin with an in-depth evaluation of your health, weight loss history, and personal goals.Customized Plan Development:
Based on your assessment, we select the best pathway—whether GLP-1 medications, HCG protocols, Prolon, or a combination—to ensure optimal outcomes.Ongoing Monitoring:
Regular check-ins help track progress, adjust your plan as needed, and monitor body composition (fat vs. muscle loss).Peptide Therapy (if needed):
If muscle loss is detected, peptide therapy may be introduced to support muscle retention and recovery.Flexible Scheduling:
Treatments like Prolon offer structured, manageable plans (e.g., 5-day cycles), while medications and other protocols are seamlessly integrated into your routine.Why Medical Supervision Matters:
Unsupervised weight loss programs can lead to nutrient deficiencies, muscle loss, and unsustainable results. With our medically guided approach, we ensure your journey is safe, effective, and supports long-term health.
Fight Against Muscle Loss
Peptide Therapy
Peptides preserve muscle mass during weight loss, especially if signs of muscle loss appear during monitoring. There are many peptides that can be used to help maintain your lean muscle mass. Most of these peptides are investigational but are very helpful.
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AOD9604 is a peptide derived from human growth hormone (HGH) fragment 176-191, itself a derivative of human growth hormone. AOD9604 is a weight loss research peptide in the truest sense of the term as it is a targeted fat burner (lipolytic) with limited additional effects.
This peptide was specifically developed to maintain the lipolytic (fat burning) fragment of growth hormone without retaining any of the parent molecules’ ability to promote lean body mass accumulation.
AOD1604 is one of the most effective peptides for weight loss research yet developed, with studies showing as much as a 50% reduction in weight gain over just three weeks of administration.
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MOTS-c is kind of unique in this list because it isn’t so much a cellular peptide as it is a mitochondrial peptide. Mitochondria are the small structures within cells that generate most of the energy cells need to function.
Research shows that MOTS-c, which is very short even among peptides for weight loss research, can penetrate the cell membrane, the mitochondrial membrane, and the nuclear membrane to affect multiple metabolic functions. MOTS-c activates the AMPK pathway to promote the burning of fat and sugar for energy production.
This is the same pathway that is activated by ketogenic diets like the Atkin’s diet. In the nucleus, MOTS-c appears to regulate genes involved in glucose utilization and antioxidant production. In particular, MOTS-c is thought to mediate beta-oxidation, thereby increase lipolysis and preventing the accumulation of new fat.
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No discussion of peptides for weight loss research would be complete without at least some mention of the large class of growth hormone (GH) secretagogues. These peptides boost levels of GH secretion from the anterior pituitary gland. High GH levels lead to increased fat burning along with enhanced muscle and bone growth. Hi GH levels also alter appetite and have been shown to increase rates of wound healing, cardiovascular fitness, bone strength, and more.
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